Neuropathy Support
Understanding Your Neuropathy Supplement Options
Dr. David Velarde, DPM prescribes Metanx as the gold-standard prescription medical food for diabetic peripheral neuropathy for all patients seen in office and via telemedicine in Tennessee. For patients outside Tennessee who cannot yet access a prescription, the wellness supplement options below contain the same core active ingredients and are available through Dr. David Velarde, DPM's Fullscript dispensary as a bridge until you can see a local podiatrist.
📞 Call 865-523-1141
Gold Standard
Metanx (Prescription)
Best for Tennessee Patients
Active Ingredients
  • L-methylfolate 3 mg
  • Pyridoxal-5-phosphate 35 mg
  • Methylcobalamin 2 mg
Key Details
  • Requires prescription
  • Insurance may cover cost
  • Cash Price Option
📞 Call 865-523-1141 to schedule your appointment.

Prescribed to all Tennessee patients — call 865-523-1141 to schedule an in-person or telemedicine visit with Dr. David Velarde, DPM.
OTC Bridge Option
Folate 5,000 Plus
Closest over-the-counter match — ideal for out-of-state patients while arranging local care.
L-Methylfolate 5 mg
Metafolin form — the same bioavailable folate used in Metanx
Pyridoxal-5-Phosphate
Active B6 form for optimal nerve support
Methylcobalamin
Active B12 form for nerve conduction and repair

No prescription needed. Patients save 10–15% via the Fullscript dispensary. Same Metafolin form as Metanx.
Enhanced Formula
Methyl Assist
Best for MTHFR Patients
An advanced formulation designed for patients with the MTHFR genetic variant or more complex neuropathy cases requiring additional nerve conduction support.
L-Methylfolate (Metafolin)
Bioavailable folate in the same Metafolin form as Metanx, at a dose calibrated for MTHFR gene conversion efficiency.
Pyridoxal-5-Phosphate
Active B6 for nerve health and neurotransmitter synthesis.
Methylcobalamin
Active B12 to support myelin sheath integrity and nerve repair.
Benfotiamine
Extra nerve conduction support — a fat-soluble thiamine derivative not found in standard Metanx.


Which Option Is Right for You?
Use the guide below to find the best path forward based on your location, diagnosis, and genetic profile.
Tennessee Patients
Call 865-523-1141 to schedule an in-person or telemedicine appointment. Dr. David Velarde, DPM will prescribe Metanx as part of your care plan.
Outside Tennessee
Order Folate 5,000 Plus or Methyl Assist through the Fullscript dispensary as a bridge while you find a local podiatrist. Use the NPI registry at nppes.cms.hhs.gov to find a licensed DPM near you.
Already on Metanx
Stay on your prescription. Do not switch to a supplement without speaking to your prescribing physician first.
MTHFR Variant Confirmed
Ask about Methyl Assist, which provides the same Metanx ingredients plus benfotiamine at a slightly higher methylfolate dose to account for reduced gene conversion efficiency.

For use under physician supervision. These statements have not been evaluated by the FDA. Supplement products are not intended to diagnose, treat, cure, or prevent any disease. Metanx is a registered trademark of Alfasigma USA Inc. Individual results vary. Dr. David Velarde, DPM may earn a commission from qualifying supplement purchases through the Fullscript dispensary. This is not a substitute for a formal podiatric evaluation.